Stack

Glow Stack

Complete Glow Stack protocol combining BPC-157, TB-500, and GHK-Cu for skin rejuvenation, anti-aging, and accelerated tissue repair. Full dosing guide.

BPC-157 TB-500 GHK-Cu

Why Stack These Three

The Glow Stack addresses tissue regeneration from three different angles. Each peptide handles a distinct phase of the repair cascade, and stacking them creates coverage that no single compound achieves alone.

PeptideWhat It DoesRole in the Stack
BPC-157Promotes angiogenesis, reduces inflammation, protects cells from damageAnti-inflammatory foundation — shields tissue while the other two rebuild
TB-500Regulates actin for cell migration, reduces fibrosis and scar tissueCell traffic control — ensures repair cells reach the right place without excess scarring
GHK-CuStimulates collagen I and III, increases elastin and GAGs, modulates 4,000+ genesMatrix builder — produces the structural proteins that make skin firm, elastic, and resilient

The synergy: BPC-157 handles acute inflammation and vascular repair. TB-500 mobilizes the cellular workforce and prevents fibrotic scarring. GHK-Cu activates the extracellular matrix rebuilding pathways and resets gene expression toward healthier, younger patterns. Together, they address inflammation, synthesis, migration, and gene regulation simultaneously.

The GHK-Cu Difference

GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is the compound that makes this stack about more than just healing. It’s a naturally occurring tripeptide-copper complex first isolated from human plasma in 1973. Serum levels average ~200 ng/mL at age 20 and drop to ~80 ng/mL by age 60 — a 60% decline that correlates with visible aging and slower healing.

What the research shows:

  • Gene expression: Influences over 4,000 human genes, resetting expression patterns toward those of younger, healthier tissue
  • Collagen synthesis: Increases collagen production by up to 70% in laboratory studies. Stimulates types I and III collagen, elastin, and glycosaminoglycans
  • Skin firmness: Clinical studies measured 20–30% improvement in skin firmness after 12 weeks. GHK-Cu produced a 31.6% reduction in wrinkle volume, outperforming Matrixyl 3000
  • Wound healing: 40–50% acceleration of wound closure vs. control treatments
  • Antioxidant activity: Reduces reactive oxygen species by ~50%. Hydroxyl radical scavenging exceeds glutathione

Full Protocol

CompoundDaily DoseFrequencyRoute
BPC-157250–500 mcgOnce dailySubcutaneous, abdomen or near target area
TB-500500–750 mcgOnce daily, or 2.0 mg twice weeklySubcutaneous, abdomen
GHK-Cu1,000–2,000 mcgOnce daily, 5 days/week (Mon–Fri)Subcutaneous, abdomen

Titration schedule:

  • Weeks 1–2: Start at the lower end of each range. BPC-157 250 mcg, TB-500 500 mcg, GHK-Cu 1,000 mcg. Assess tolerance.
  • Weeks 3+: Increase to full dose if no issues. BPC-157 500 mcg, TB-500 750 mcg, GHK-Cu 2,000 mcg.

Pre-Blended GLOW Vial (Convenient Option)

Pre-blended vials (typically 70 mg total) use a 5:1:1 ratio:

CompoundPer Injection
GHK-Cu~1,700 mcg
TB-500~330 mcg
BPC-157~330 mcg
Total~2,330 mcg

Add 3.0 mL bacteriostatic water for ~23.3 mg/mL concentration. Inject 10 units (0.10 mL) per day on a U-100 insulin syringe.

Cycle Structure

  • Cycle length: 8–12 weeks on individual vials. 4 weeks on the pre-blended vial (repeat for 2–3 cycles).
  • Rest period: 4 weeks off between cycles. Essential for receptor sensitivity and to prevent copper accumulation from GHK-Cu.
  • Injection timing: Morning or evening — consistency matters more than time of day. All three can be injected in the same session.
  • Injection sites: Abdomen, thigh, or upper arm. Rotate systematically with 1–2 inch spacing.

Who This Stack Is For

  • Skin health focus — firmness, elasticity, texture improvement
  • Anti-aging biohackers — collagen and elastin synthesis support, gene-level rejuvenation
  • Post-procedure recovery — after microneedling, PRP, or cosmetic procedures
  • Athletes with soft tissue injuries — all the healing of the Wolverine Stack plus skin repair
  • Slow healers — anyone noticing age-related decline in wound healing or recovery

Results Timeline

Weeks 1–2: Early Signals

  • Reduced inflammation at injury sites (BPC-157)
  • Improved skin hydration and texture (GHK-Cu)
  • Better sleep quality (commonly reported)

Weeks 3–6: Visible Changes

  • Noticeable improvement in skin firmness and elasticity
  • Wound healing acceleration
  • Reduced joint stiffness and pain
  • Hair and nail quality improvements

Weeks 8–12: Deep Remodeling

  • Measurable increase in collagen density
  • Wrinkle reduction (especially fine lines)
  • Structural tissue repair completing
  • Effects from GHK-Cu persist 2–4 months post-cycle

Safety

Side Effects

Generally mild and transient:

  • Injection-site redness or itching (most common, resolves within hours)
  • Transient fatigue or mild headache in the first few days
  • Light nausea (rare)

Copper Considerations

GHK-Cu delivers copper with each injection. The body tightly regulates copper and excretes excess through bile, so toxicity at standard doses is extremely unlikely. However:

  • Cycle off after 8–12 weeks to prevent accumulation
  • Do not use if you have Wilson’s Disease or other copper metabolism disorders
  • A baseline copper and ceruloplasmin level is prudent for longer protocols

Standard Contraindications

  • Active cancer or tumor history (all three peptides promote angiogenesis)
  • Pregnancy or breastfeeding
  • Under 18
  • Blood clotting disorders or anticoagulant therapy
  • Tested athletes (BPC-157 and TB-500 are WADA-banned)

What Comes Next

After your first Glow Stack cycle:

  • Repeat the cycle after a 4-week rest for deeper results
  • Add topical GHK-Cu serum or cream alongside injections for surface-level skin targeting
  • Explore the Wolverine Stack if your primary goal shifts to injury recovery
  • Review individual protocols for BPC-157 and GHK-Cu if you want to run compounds solo

Frequently Asked Questions

What is the Glow Stack? +

The Glow Stack combines BPC-157, TB-500, and GHK-Cu — three peptides targeting different phases of tissue repair and regeneration. BPC-157 handles inflammation and local healing, TB-500 drives cell migration and prevents scarring, and GHK-Cu stimulates collagen and elastin synthesis while resetting gene expression toward younger patterns.

How long until I see skin improvements? +

Most users report noticeable improvements in skin texture and firmness within 2–4 weeks. Deeper changes in collagen density and wrinkle reduction typically require 8–12 weeks. GHK-Cu effects persist 2–4 months after completing a cycle.

Should I use the pre-blended vial or separate vials? +

Pre-blended GLOW vials (typically 70 mg total in a 5:1:1 ratio) are more convenient — one injection per day. Separate vials let you adjust each compound independently. If this is your first cycle, separate vials give you more control to dial in the right dose for your goals.

What are the side effects of the Glow Stack? +

The most common side effect is mild injection-site irritation that resolves within hours. Some users report transient fatigue, mild headache, or light nausea in the first few days. No serious adverse events have been documented at standard doses.

Can I combine the Glow Stack with topical GHK-Cu? +

Yes. Many users combine subcutaneous GHK-Cu injection for systemic benefits with topical application (cream or serum) for targeted skin improvement. The routes address different tissue depths. Monitor total copper intake and don't exceed recommended dosing.

Stack Overview

Goal Skin Rejuvenation, Anti-Aging & Tissue Repair
Cycle Length 8–12 weeks on, 4 weeks off
BPC-157 250–500 mcg/day · Once daily

Anti-inflammatory foundation and localized tissue repair

TB-500 500–750 mcg/day · Once daily (or 2 mg twice weekly)

Cell migration, tissue remodeling, scar tissue prevention

GHK-Cu 1,000–2,000 mcg/day · Once daily, 5 days/week

Collagen synthesis, elastin production, gene-level rejuvenation